Charles River Laboratories International, Inc. (CRL)

業務介紹

查爾斯河實驗室國際有限公司是一家非臨床合同研究機構，提供藥物發現、非臨床開發和安全性測試服務，業務遍及美國、歐洲、加拿大、亞太地區和國際市場。公司分為三個業務板塊：研究模型和服務（RMS）、發現和安全評估（DSA）以及製造解決方案（Manufacturing）。RMS業務板塊生產和銷售用於研究的啮齒動物模型品系和特殊培育的大鼠和小鼠。該業務板塊還提供一系列服務，以幫助客戶在研究和篩選非臨床藥物候選物時支持研究模型的使用，包括研究模型、基因工程模型和服務、內部外包解決方案以及研究動物診斷服務。DSA業務板塊提供早期和體內發現服務，用於識別和驗證新靶點、化學化合物和抗體，並提供非臨床藥物和治療候選物的安全評估；同時提供毒理學、病理學、安全藥理學、生物分析、藥物代謝和藥物動力學等安全評估服務。製造業務板塊提供體外方法，用於對無菌和非無菌藥品和消費品進行常規和快速質量控制測試。該業務板塊還提供由製藥和生物技術公司外包的生物製劑的專業測試；以及供製造疫苗使用的無特定病原（SPF）育種雞蛋、SPF雞和診斷產品的禽類疫苗服務。該公司還為生物製藥客戶提供合同動物房運營服務。查爾斯河實驗室國際有限公司成立於1947年，總部位於馬薩諸塞州威爾明頓市。

Charles River Laboratories International, Inc., a non-clinical contract research organization, provides drug discovery, non-clinical development, and safety testing services in the United States, Europe, Canada, the Asia Pacific, and internationally. It operates through three segments: Research Models and Services (RMS), Discovery and Safety Assessment (DSA), and Manufacturing Solutions (Manufacturing). The RMS segment produces and sells rodent research model strains and purpose-bred rats and mice for use by researchers. This segment also provides a range of services to assist its clients in supporting the use of research models in research and screening non-clinical drug candidates, including research models, genetically engineered models and services, insourcing solutions, and research animal diagnostic services. The DSA segment offers early and in vivo discovery services for the identification and validation of novel targets, chemical compounds, and antibodies through delivery of non-clinical drug and therapeutic candidates ready for safety assessment; and safety assessment services, such as toxicology, pathology, safety pharmacology, bioanalysis, drug metabolism, and pharmacokinetics services. The Manufacturing segment provides in vitro methods for conventional and rapid quality control testing of sterile and non-sterile pharmaceuticals and consumer products. This segment also offers specialized testing of biologics that are outsourced by pharmaceutical and biotechnology companies; and avian vaccine services that provide specific-pathogen-free (SPF) fertile chicken eggs, SPF chickens, and diagnostic products used to manufacture vaccines. The company also provides contract vivarium operation services to biopharmaceutical clients. Charles River Laboratories International, Inc. was founded in 1947 and is headquartered in Wilmington, Massachusetts.

公司網址

https://www.criver.com